Tablets containing açaí (Euterpe spp.) dried extract for dietary supplementation: A study of functional properties
DOI:
https://doi.org/10.5327/fst.00052Palavras-chave:
drying technology, direct compression, cyanidin-3-rutinoside, LC-MS, spray drying, mechanical propertyResumo
Açaí is a very popular functional food in the Amazon due to its nutritional properties, its high caloric value, and its high content of anthocyanins and phenolic compounds, which mainly confers antioxidant and anti-inflammatory activities. Thus, this study aimed at the development of immediate-release tablets containing açaí dried extract by direct compression. The extract was subjected to physical evaluation of the powder, quantification of total polyphenol (TP) content (mg EAG/g), total anthocyanin content (mg C3G/100 g), cyanidin-3-rutinoside marker (µg C3R/g) by LC-MS, obtention of the tablet, and their physical-mechanical evaluation. Açaí dried extract showed spherical shape particles, with smooth and rough surfaces and heterogeneous sizes, which are characteristic of dried powders when obtained by spray drying. In addition, the extract presented TP content (23.307± 2.190 mg EAG/g), total anthocyanins (10.52 mg C3G/100 g), and cyanidin-3-rutinoside (42 µg C3R/g). Tablets had good mechanical properties, good thermal stability under 200°C, and 3.65 µg C3R/g of cyanidin-3-rutinoside content per tablet unit. The results obtained in this study showed the possibility of obtaining tablets containing açaí dried extract with good mechanical properties and antioxidant activity aiming its use as a dietary supplement.
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Referências
Agência Nacional de Vigilância Sanitária (ANVISA) (2018). Resolução da Diretoria Colegiada - RDC nº 243, de 26 de julho de 2018. Dispõe sobre os requisitos sanitários dos suplementos alimentares. Diário Oficial da União, (144).
Aliakbarian, B., Casazza, A. A., & Perego, P. (2011). Valorization of olive oil solid waste using high pressure-high temperature reactor. Food Chemistry, 128(3), 704-710. https://doi.org/10.1016/j.foodchem.2011.03.092
Borges, G. D. S. C., Vieira, F. G. K., Copetti, C., Gonzaga, L. V., & Fett, R. (2011). Optimization of the extraction of flavanols and anthocyanins from the fruit pulp of Euterpe edulis using the response surface methodology. Food Research International, 44(3), 708-715. https://doi.org/10.1016/j.foodres.2010.12.025
Carvalho, A. V., Ferreira Ferreira da Silveira, T., Mattietto, R. de A., Padilha de Oliveira, M. do S., & Godoy, H. T. (2017). Chemical composition and antioxidant capacity of açaí (Euterpe oleracea) genotypes and commercial pulps. Journal of the Science of Food and Agriculture, 97(5), 1467-1474. https://doi.org/10.1002/jsfa.7886
Chandrasekhar, J., Madhusudhan, M. C., & Raghavarao, K. S. M. S. (2012). Extraction of anthocyanins from red cabbage and purification using adsorption. Food and Bioproducts Processing, 90(4), 615-623. https://doi.org/10.1016/j.fbp.2012.07.004
Cianchino, V. A., Favier, L. S., Ortega, C. A., Peralta, C., & Cifuente, D. A. (2020). Formulation development and evaluation of Silybum marianum tablets. Rodriguésia, 71. https://doi.org/10.1590/2175-7860202071044
Costa, R. G., Andreola, K., de Andrade Mattietto, R., de Faria, L. J. G. & Taranto, O. P. (2015). Effect of operating conditions on the yield and quality of açai (Euterpe oleracea Mart.) powder produced in spouted bed. LWT - Food Science and Technology, 64(2), 1196-1203. https://doi.org/10.1016/j.lwt.2015.07.027
da Silva Carvalho, A. G., da Costa Machado, M. T., da Silva, V. M., Sartoratto, A., Rodrigues, R. A. F., & Hubinger, M. D. (2016). Physical properties and morphology of spray dried microparticles containing anthocyanins of jussara (Euterpe edulis Martius) extract. Powder Technology, 294, 421-428. https://doi.org/10.1016/j.powtec.2016.03.007
da Silveira, T. F. F., Cristianini, M., Kuhnle, G. G., Ribeiro, A. B., Filho, J. T., & Godoy, H. T. (2019). Anthocyanins, non-anthocyanin phenolics, tocopherols and antioxidant capacity of açaí juice (Euterpe oleracea) as affected by high pressure processing and thermal pasteurization. Innovative Food Science and Emerging Technologies, 55, 88-96. https://doi.org/10.1016/j.ifset.2019.05.001
Fang, Z., & Bhandari, B. (2011). Effect of spray drying and storage on the stability of bayberry polyphenols. Food Chemistry, 129(3), 1139-1147. https://doi.org/10.1016/j.foodchem.2011.05.093
Fernandes, R. V. de B., Botrel, D. A., Silva, E. K., Borges, S. V., Oliveira, C. R. de, Yoshida, M. I., Feitosa, J. P. de A., & de Paula, R. C. M. (2016). Cashew gum and inulin: New alternative for ginger essential oil microencapsulation. Carbohydrate Polymers, 153, 133-142. https://doi.org/10.1016/J.CARBPOL.2016.07.096
Franceschinis, L., Salvatori, D. M., Sosa, N., & Schebor, C. (2014). Physical and Functional Properties of Blackberry Freeze- and Spray-Dried Powders. Drying Technology, 32(2), 197-207. https://doi.org/10.1080/07373937.2013.814664
Ghribi, A. M., Gafsi, I. M., Blecker, C., Danthine, S., Attia, H., & Besbes, S. (2015). Effect of drying methods on physico-chemical and functional properties of chickpea protein concentrates. Journal of Food Engineering, 165, 179-188. https://doi.org/10.1016/j.jfoodeng.2015.06.021
Giusti, M. M., & Wrolstad, R. E. (2001). Characterization and Measurement of Anthocyanins by UV-Visible Spectroscopy. Current Protocols in Food Analytical Chemistry. https://doi.org/10.1002/0471142913.faf0102s00
Laokuldilok, T., & Kanha, N. (2015). Effects of processing conditions on powder properties of black glutinous rice (Oryza sativa L.) bran anthocyanins produced by spray drying and freeze drying. LWT - Food Science and Technology, 64(1), 405-411. https://doi.org/10.1016/J.LWT.2015.05.015
Loureiro Contente, D. M., Pereira, R. R., Rodrigues, A. M. C., da Silva, E. O., Ribeiro-Costa, R. M., & Carrera Silva-Júnior, J. O. (2020). Nanoemulsions of Acai Oil: Physicochemical Characterization for the Topical Delivery of Antifungal Drugs. Chemical Engineering and Technology, 43(7), 1424-1432. https://doi.org/10.1002/ceat.201900627
Magalhães, T. S. S. de A., Macedo, P. C. de O., Converti, A., & de Lima, Á. A. N. (2020). The use of euterpe oleracea mart. As a new perspective for disease treatment and prevention. Biomolecules, 10(6), 813. https://doi.org/10.3390/biom10060813
Nascimento, R. J. S. do, Couri, S., Antoniassi, R., & Freitas, S. P. (2008). Composição em ácidos graxos do óleo da polpa de açaí extraído com enzimas e com hexano. Revista Brasileira de Fruticultura, 30(2), 498-502. https://doi.org/10.1590/S0100-29452008000200040
Osorio, C., Forero, D. P., & Carriazo, J. G. (2011). Characterisation and performance assessment of guava (Psidium guajava L.) microencapsulates obtained by spray-drying. Food Research International, 44(5), 1174-1181. https://doi.org/10.1016/J.FOODRES.2010.09.007
Paim, D. R. S. F., Costa, S. D. O., Walter, E. H. M., & Tonon, R. v. (2016). Microencapsulation of probiotic jussara (Euterpe edulis M.) juice by spray drying. LWT, 74, 21-25. https://doi.org/10.1016/J.LWT.2016.07.022
Park, S., Valan Arasu, M., Lee, M. K., Chun, J. H., Seo, J. M., Lee, S. W., Al-Dhabi, N. A., & Kim, S. J. (2014). Quantification of glucosinolates, anthocyanins, free amino acids, and vitamin C in inbred lines of cabbage (Brassica oleracea L.). Food Chemistry, 145, 77-85. https://doi.org/10.1016/J.FOODCHEM.2013.08.010
Paul, S., & Sun, C. C. (2018). Systematic evaluation of common lubricants for optimal use in tablet formulation. European Journal of Pharmaceutical Sciences, 117, 118-127. https://doi.org/10.1016/J.EJPS.2018.02.013
Rufino, M. do S. M., Alves, R. E., de Brito, E. S., Pérez-Jiménez, J., Saura-Calixto, F., & Mancini-Filho, J. (2010). Bioactive compounds and antioxidant capacities of 18 non-traditional tropical fruits from Brazil. Food Chemistry, 121(4), 996-1002. https://doi.org/10.1016/J.FOODCHEM.2010.01.037
Santamarina, A. B., Jamar, G., Mennitti, L. V., Ribeiro, D. A., Cardoso, C. M., Vera De Rosso, V., Oyama, L. M., Pisani, L. P., & Maione, F. (2019). Polyphenols-Rich Fruit (Euterpe edulis Mart.) Prevents Peripheral Inflammatory Pathway Activation by the Short-Term High-Fat Diet. Molecules, 24(9), 1655. https://doi.org/10.3390/molecules24091655
Schulz, M., Tischer Seraglio, S. K., Gonzaga, L. V., Costa, A. C. O., & Fett, R. (2021). Phenolic Compounds in Euterpe Fruits: Composition, Digestibility, and Stability–A Review. Food Reviews International, 39(1), 369-396. https://doi.org/10.1080/87559129.2021.1909060
Silva da Costa, R., Pinheiro, W. B. de S., Arruda, M. S. P., Costa, C. E. F., Converti, A., Ribeiro Costa, R. M., & Silva Júnior, J. O. C. (2022). Thermoanalytical and phytochemical study of the cupuassu (Theobroma grandiflorum Schum.) seed by-product in different processing stages. Journal of Thermal Analysis and Calorimetry, 147(1), 275-284. https://doi.org/10.1007/s10973-020-10347-0
Simon-Brown, K., Solval, K. M., Chotiko, A., Alfaro, L., Reyes, V., Liu, C., Dzandu, B., Kyereh, E., Goldson Barnaby, A., Thompson, I., Xu, Z., & Sathivel, S. (2016). Microencapsulation of ginger (Zingiber officinale) extract by spray drying technology. LWT - Food Science and Technology, 70, 119-125. https://doi.org/10.1016/j.lwt.2016.02.030
Tonon, R. v., Brabet, C., & Hubinger, M. D. (2008). Influence of process conditions on the physicochemical properties of açai (Euterpe oleraceae Mart.) powder produced by spray drying. Journal of Food Engineering, 88(3), 411-418. https://doi.org/10.1016/J.JFOODENG.2008.02.029
Tonon, R. v., Brabet, C., & Hubinger, M. D. (2010). Anthocyanin stability and antioxidant activity of spray-dried açai (Euterpe oleracea Mart.) juice produced with different carrier agents. Food Research International, 43(3), 907-914. https://doi.org/10.1016/J.FOODRES.2009.12.013
Tonon, R. v., Brabet, C., Pallet, D., Brat, P., & Hubinger, M. D. (2009). Physicochemical and morphological characterisation of açai (Euterpe oleraceae Mart.) powder produced with different carrier agents. International Journal of Food Science and Technology, 44(10), 1950-1958. https://doi.org/10.1111/J.1365-2621.2009.02012.X
Valente, M. da C. da C., do Nascimento, R. A., Santana, E. B., Ribeiro, N. F. da P., Costa, C. M. L., & de Faria, L. J. G. (2019). Spray drying of extract from Euterpe oleracea Mart.: Optimization of process and characterization of the açaí powder. Journal of Food Process Engineering, 42(8), e13253. https://doi.org/10.1111/jfpe.13253
Yamaguchi, K. K. D. L., Pereira, L. F. R., Lamarão, C. V., Lima, E. S., & da Veiga-Junior, V. F. (2015). Amazon acai: Chemistry and biological activities: A review. Food Chemistry, 179, 137-151. https://doi.org/10.1016/J.FOODCHEM.2015.01.055