Contributions of Cucumis L. Genetic diversity to phytochemical bioavailability and its impact on human health: A review

Autores

  • Clemilson Elpidio da Silva Universidade Estadual de Campinas, Faculty of Food Engineering, Department of Food Science and Nutrition, Campinas, São Paulo, Brazil. https://orcid.org/0000-0002-0043-0559
  • Maria Teresa Pedrosa Silva Clerici Universidade Estadual de Campinas, Faculty of Food Engineering, Department of Food Science and Nutrition, Campinas, São Paulo, Brazil. https://orcid.org/0000-0002-8445-336X

DOI:

https://doi.org/10.5327/fst.491

Palavras-chave:

Cucurbitaceae, healthiness, antioxidant compounds, dietary fiber, toxicity, safety

Resumo

The genus Cucumis L., belonging to the Cucurbitaceae family, is home to a diversity of species of economic and nutritional importance, with cucumber (C. sativus L.), melon (C. melo L.), maxixe (C. anguria L.), and kiwano melon or horned cucumber (C. metuliferus E.) being the best-known species in Brazil. These fruits represent a significant source of nutrients and ingredients for the food, pharmaceutical, and ethnopharmacological industries. This article provides an overview of the chemical characteristics, nutritional composition, and applications of the genus Cucumis L., addressing its diversity, geographical distribution, economic importance, traditional and potential uses, as well as the challenges and future prospects for research and development of new products.

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Referências

Abubakar, A., Iliyasu, B., Ojiegbu, F. N., Igweh, A. C., Shamaki, B. U., Dung, E. C., Domtur, L. L., Okogun, J. I., Gbodi, T. A,. & Ogbadoyi, E. O. (2011). Evaluation of the antitrypanosomal activity of the pulp extract of Cucumis metuliferus pulp extract in rabbits. Journal of Medicinal Plant Research, 5(11), 2136–2142. https://doi.org/10.5897/JMPR.9000637

Ajuru M., & Nmom F. (2017). A review on the economic uses of species of Cucurbitaceae and their sustainability in Nigeria. Journal of Plant Biology, 2(1),17–24. https://doi.org/10.11648/j.ajpb.20170201.14

Albuquerque, J. R. T., Sá, F. V. S., Oliveira, F. A., Paiva, E. P., Araújo, E. B. G., & Souto, L. S. (2016). Initial growth and tolerance of cucumber cultivars under saline stress. Brazilian Journal of Agriculture, 10(2), 486–495. https://doi.org/10.7127/rbai.v10n200355

Ani, N. O., & Achikanu, C. E. (2021). Phytochemical and Vitamin Composition of Cucumis metuliferus Juice. Asian Journal of Biochemistry, Genetics and Molecular Biology, 9(4), 92–98. https://doi.org/10.9734/ajbgmb/2021/v9i430232

Anon, A. (2009). Mienkie Welman National Herbarium, Pretoria. Retrieved October 14, 2024, from http://www.plantzafrica.com/planted/Cucumismet.htm

Ayres, E. M. M., Lee, S. M., Boyden, L., & Guinard, J.-X. (2019). Sensory Properties and Consumer Acceptance of Cantaloupe Melon Cultivars. Journal of Food Science, 84(8), 2278–2288. https://doi.org/10.1111/1750-3841.14724

Barroso, A. B. (2021). Non-conventional food plants of the Northeast: a review [Undergraduate thesis, Universidade Federal do Ceará]. http://repositorio.ufc.br/handle/riufc/61758

Bieski, I. G. C, Leonti, M., Arnason, J. T., Ferrier, J., Rapinski, M., Violante, I. M. P., Balogun, S. O., Pereira, J. F. C. A., Figueiredo, R. C. F., Lopes, C. R. A. S., Silva, D. R., Pacini, A., Albuquerque, & Martins, D. T. O. (2015). Ethnobotanical study of medicinal plants by population of valley of Juruena region, legal Amazon, Mato Grosso, Brazil. Journal of Ethnopharmacology, 173, 383–423. https://doi.org/10.1016/j.jep.2015.07.025

Brasil. (2011). Standardization of cucumber. Ministry of Agriculture, Livestock and Food Supply. Retrieved April 6, 2024, from http://extranet.agricultura.gov.br/sislegisconsulta/servlet/VisualizarAnexo?id=7196>

Busuioc, A. C., Costea, G. V., Botezatu, A. V. D., Furdui, B., & Dinica, R. M. (2023). Cucumis metuliferus L. Fruits Extract with Antioxidant, Anti-Inflammatory, and Antidiabetic Properties as Source of Ursolic Acid. Separations, 10(5), Article 274. https://doi.org/10.3390/separations10050274

Camargo, A. M. M. P., Camargo, F.P., & Camargo Filho, W.P. (2008). Geographic Distribution of Vegetable Production in the State of São Paulo: participation in the country, regional concentration and evolution in the period 1996-2006. Informações Econômicas, 38(1), 28–35. https://iea.agricultura.sp.gov.br/ftpiea/ie/2008/tec3-0108.pdf

Canva. (2024). Infographic on the geographical distribution of the genus Cucumis L. in Brazil. Free templates. Retrieved December 15, 2024, from https://www.canva.com/infographics/templates/science/

Christenhusz, M. J. M., & Byng, J. W. (2016). The number of known plants species in the world and its annual increase. Phytotaxa, 261(3), 201–217. https://doi.org/10.11646/phytotaxa.261.3.1

Chung, I.-M., Rajakumar, G., Gomathi, T., Park, S.-K., Kim, S.-H., & Thiruvengadam, M. (2017). Nanotechnology for human food: Advances and perspective. Frontiers in Life Science, 10(1), 63–72. https://doi.org/10.1080/21553769.2017.1365775

Dar, A. A., Mahajan, R., Lay, P., & Sharma, S. (2017). Genetic diversity and population structure of Cucumis sativus L. by using SSR markers. 3 Biotech, 7(5), Article 307. https://doi.org/10.1007/s13205-017-0944-x

Dhiman, K., Gupta, A., Sharma, D. K., Gill, N. S., & Goyal A. (2012). A Review on the medicinally important plants of the family Cucurbitaceae. Asian Journal of Clinical Nutrition, 4(1), 16–26. https://doi.org/10.3923/ajcn.2012.16.26

Dzomba, P., & Mupa, M. (2012). Wild Cucumis anguria leaves: phytochemical profile and antioxidant capacity. Asian Pacific Journal of Tropical Biomedicine, 1, 1–5. https://www.researchgate.net/publication/235699064_Wild_Cucumis_anguria_leaves_phytochemical_profile_and_antioxidant_capacity#:~:text=Analysis%20of%20the%20phytochemicals%20found,Dzomba%20and%20Mupa%2C%202012)%20.

Empresa Brasileira de Pesquisa Agropecuária. (2017). A cultura do melão [The melon culture] (3rd ed.). Embrapa.

Fathalipour, M., Fathalipour, H., Safa, O., Nowrouzi-Sohrabi, P., Mirkhani, H., & Hassanipour, S. (2020). The Therapeutic Role of Carotenoids in Diabetic Retinopathy: A Systematic Review. Diabetes, Metabolic Syndrome and Obesity, 13, 2347–2358. https://doi.org/10.2147/DMSO.S255783

Ferrara, L. (2018). A fruit to discover: Cucumis metuliferus E.Mey Ex Naudin(Kiwano). Clinical Nutrition and Metabolism, 5, 1–2. https://doi.org/10.15761/CNM.1000109

Figueirêdo, M. C. B., Gondim, R. S., & Aragão, F. A. S. (Eds.). (2017). Produção de Melão e mudanças climáticas: Sistemas conservacionistas de cultivo para redução das pegadas de carbono e hídrica [Melon production and climate change: conservationist cultivation systems to reduce carbon and water footprints]. Embrapa. http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1074500

Food and Agriculture Organization of the United Nations. (2020). Countries by commodity. Retrieved January 18, 2025, from https://www.fao.org/faostat/en/#rankings/countries_by_commodity

Food and Agriculture Organization of the United Nations. (2023). World Food and Agriculture – Statistical Yearbook 2023. FAO. https://doi.org/10.4060/cc8166en

Gomes-Klein, V. L., Lima, L. F. P., Gomes-Costa, G. A., & Medeiros, E. S. (2015). Cucurbitaceae In: Lista de Espécies da Flora do Brasil. Jardim Botânico do Rio de Janeiro. Retrieved January 14, 2025, from https://floradobrasil2015.jbrj.gov.br/FB82117

Gotep, J. (2011). Glycosides fraction extracted from fruit pulp of Cucumis metuliferus E. Meyer has antihyperglycemic effect in rats with alloxan-induced diabetes. Journal of Natural Pharmaceuticals, 2(2), 48. https://go.gale.com/ps/i.do?id=GALE%7CA265947122&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=22295119&p=AONE&sw=w&cookieConsent=true&analyticsOptout=false&userGroupName=anon%7Ef8e0005b&aty=open-web-entry

Hashemi, S. M. B., Gholamhosseinpour, A., & Niakousari, M. (2019). Application of microwave and ohmic heating for pasteurization of cantaloupe juice: microbial inactivation and chemical properties. Journal of the Science of Food and Agriculture, 99(9), 4276–4286. https://doi.org/10.1002/jsfa.9660

Instituto Brasileiro de Geografia e Estatística. (2024). Produção de Melão: Rio Grande do Norte [Melon production in the state of Rio Grande do Norte]. Retrieved January 12, 2025, from https://www.ibge.gov.br/explica/producao-agropecuaria/melao/rn

Jeyakumar, J. J., Kamaraj, M., & Thiruvengadam, M. (2014). Efficient plant regeneration from petiole explants of West Indian gherkin (Cucumis anguria L.) via indirect organogenesis. Journal of Plant Biochemistry and Biotechnology, 23(3), 307–315. https://doi.org/10.1007/s13562-013-0215-9

Jimam, N., Omale, S., Wannang, N., & Gotom, B. (2010). Evaluation of the Hypoglycemic Activity of Cucumis metuliferus (Cucurbitaceae) Fruit Pulp Extract in Normoglycemic and Alloxan-Induced Hyperglycemic Rats. Journal of Young Pharmacists, 2(4), 384–387. https://doi.org/10.4103/0975-1483.71633

Kaleem, M. M., Nawaz, M. A., Ding, X., Wen, S., Shireen, F., Cheng, J., & Bie, Z. (2022). Comparative analysis of pumpkin rootstocks mediated impact on melon sensory fruit quality through integration of non-targeted metabolomics and sensory evaluation. Plant Physiology and Biochemistry, 192, 320–330. https://doi.org/10.1016/j.plaphy.2022.10.010

Kesh, H., & Kaushik, P. (2021). Advances in melon (Cucumis melo L.) breeding: An update. Science and Horticulturae, 282, Article 110045. https://doi.org/10.1016/j.scienta.2021.110045

Kimathi, P. K., Maitho, T., Mbaria, J., & Moriasi, G. (2022). Antidiarrheal, antimicrobial, and toxic effects of the aqueous and methanolic leaf and fruit extracts of Cucumis dipsaceus (Ehrenb. Ex Spach.). Journal of Herbmed Pharmacology, 11(2), 213–225. https://doi.org/10.34172/jhp.2022.26

Kumar, D., Kumar, S., Singh, J., Narender, Rashmi, Vashistha, B. D., & Singh, N. (2010). Free Radical Scavenging and Analgesic Activities of Cucumis sativus L. Fruit Extract. Journal of Young Pharmacists, 2(4), 365–368. https://doi.org/10.4103/0975-1483.71627

Kumar, S., & Kamaraj, M. (2010). Analysis of phytochemical constituents and antimicrobial activities of Cucumis anguri. L. against clinical pathogens. American Eurasian Journal of Agricultural Environmental Science, 7(2), 176–178. http://idosi.org/aejaes/jaes7(2)/9.pdf

Lecholocholo, N., Shoko, T., Manhivi, V. E., Maboko, M. M., Akinola, S. A., & Sivakumar, D. (2022). Influence of different rootstocks on quality and volatile constituents of cantaloupe and honeydew melons (Cucumis melo. L) grown in high tunnels. Food Chemistry, 393, Article 133388. https://doi.org/10.1016/j.foodchem.2022.133388

Lima, L. F. P. (2010). Taxonomic and morphopollinic studies in Brazilian Curcubitaceae [Doctoral thesis, Universidade Federal do Rio Grande do Sul]. http://hdl.handle.net/10183/26294

Lima, L. F. P. (2022). Cucumis in Flora e Funga do Brasil. Jardim Botânico do Rio de Janeiro [Cucumis in Flora and Fungi of Brazil. Botanical Garden of Rio de Janeiro]. Retrieved December 15, 2024, from https://floradobrasil.jbrj.gov.br/FB82116

Magalhães, K. N., Guarniz, W. A. S., Sá, K. M., Freire, A. B., Monteiro, M. P., Nojosa, R. T., Bieski, I. G. C., Custódio, J. B., Balogun, S. O., & Bandeira, M. A. M. (2019). Medicinal plants of the Caatinga, northeastern Brazil: Ethnopharmacopeia (1980–1990) of the late professor Francisco José de Abreu Matos. Journal of Ethnopharmacology, 237, 314–353. https://doi.org/10.1016/j.jep.2019.03.032

Matsusaka, Y., & Kawabata, J. (2010). Evaluation of antioxidant capacity of non-edible parts of some selected tropical fruits. Food Science and Technology Research, 16(5), 467–472. https://doi.org/10.3136/fstr.16.467

Medeiros, A. K. O. C., Gomes, C. C., Amaral, M. L. Q. A., Medeiros, L. D. G., Medeiros, I., Porto, D. L., Aragão, C. F. S., Maciel, B. L. M., Morais, A. H. M., & Passos, T. S. (2019). Nanoencapsulation improved water solubility and color stability of carotenoids extracted from Cantaloupe melon (Cucumis melo L.). Food Chemistry, 270, 562–572. https://doi.org/10.1016/j.foodchem.2018.07.099

Medeiros, L. D. G., Carvalho, L. B. A., Freitas, E. P. S., Porto, D. L., Aragão, C. F. S., Sousa Júnior, F. C., Damasceno, K. S. F. S. C., Assis, C. F., Morais, A. H. A., & Passos, T. S. (2024). Alternative flours from pulp melons (Cucumis melo L.): Seasonality influence on physical, chemical, technological parameters, and utilization in bakery product. Heliyon, 10(9), Article e29609. https://doi.org/10.1016/j.heliyon.2024.e29609

Milind, P., & Kulwant, S. (2011). Musk melon is eat-must melon. The International Research Journal of Pharmacy, 2(8), 52–57. https://www.researchgate.net/publication/266892031_Musk_melon_is_eat-must_melon

Mondal A., Maity, T. K., & Bishayee, A. (2019). Analgesic and Anti-Inflammatory Activities of Quercetin-3-methoxy-4'-glucosyl-7-glucoside Isolated from Indian Medicinal Plant Melothria heterophylla. Medicines, 6(2), Article 59. https://doi.org/10.3390/medicines6020059

Morais, D. R., Rotta, E. M., Sargi, S. C., Bonafe, E. G., Suzuki, R. M., Souza, N. E., Matsushita, M., & Visentainer, J. V. (2017). Proximate composition, mineral contents and fatty acid composition of the different parts and dried peels of tropical fruits cultivated in Brazil. Journal of the Brazilian Chemical Society, 28(2), Article 30818. https://doi.org/10.5935/0103-5053.20160178

Moreira, H. J. C., & Bragança, H. B. N. (2011). Manual de Identificação de Plantas Infestantes: Hortifrúti. FMC Agricultural Products. http://www.cana.com.br/biblioteca/informativo/DOC-20160905-WA0023.pdf

Moretoni, C. B. (2008). Avaliação fitoquímica e das atividades antioxidante, citotóxica e hipoglicemiante dos frutos de Cucumis anguria L.(Cucurbitaceae) [Master's dissertation, Universidade Federal do Paraná]. https://hdl.handle.net/1884/17950

Morgia, L., Russo, G. I., Urzi, D., Privitera, S., Castelli, T., Favilla, V., & Cimino, S. (2017). A phase II, randomized, single-blinded, placebo-controlled clinical trial on the efficacy of Curcumina and Calendula suppositories for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome type III. Archivo Italiano di Urologia e Andrologia, 89(2), 110–113. https://doi.org/10.4081/aiua.2017.2.110

Muller, N. G., Fasolo, D., Pinto, F. P., Bertê, R., & Muller, F. C. (2013). Phytochemical potentialities of melon (Cucumis melo L.) in the northwest region of Rio Grande do Sul - Brazil. Revista Brasileira de Plantas Medicinais, 15(2), 194–198. https://doi.org/10.1590/S1516-05722013000200005

Mzena, T., Swai, H., & Chacha, M. (2018). Antimalarial activity of Cucumis metuliferus and Lippia kituiensis against Plasmodium berghei infection in mice. Research and Reports in Tropical Medicine, 9, 81–88. https://doi.org/10.2147/rrtm.s150091

Nagashima, Y., He, K., Singh, J., Metrani, R., Crosby, K.M., Jifon, J., Jayaprakasha, G. K., Patil, B., Qian, X., & Koiwa, H. (2021). Transition of aromatic volatile and transcriptome profiles during melon fruit ripening. Plant Science, 304, Article 110809. https://doi.org/10.1016/j.plantsci.2020.110809

Nascimento, L., Oliveira, F. A., Silva, D. D., Tomaz, F. L. S., Nunes, G. H. S, & Oliveira, F. H. T. (2023). Efficiency of phosphorus use by melon genotypes. Brazilian Journal of Agricultural and Environmental Engineering, 27(1), 9–17. https://doi.org/10.1590/1807-1929/agriambi.v27n1p9-17

Oboh, G., Ademosun, A. O., Olumuyiwa, T. A., Olasehinde, T. A., Ademiluyi, A. O., & Adeyemo, A. C. (2017). Insecticidal activity of essential oil from orange peels (Citrus sinensis) against Tribolium confusum, Callosobruchus maculatus and Sitophilus oryzae and its inhibitory effects on acetylcholinesterase and Na+/K+-ATPase activities. Phytoparasitica, 45(4), 501–508. https://doi.org/10.1007/s12600-017-0620-z

Odhav, B., Beekrum, S., Akula, U., & Baijnath, H. (2007). Preliminary assessment of nutritional value of traditional leafy vegetables in KwaZulu-Natal, South Africa. Journal of Food Composition and Analysis, 20(5), 430–435. https://doi.org/10.1016/j.jfca.2006.04.015

Omale, S., Wuyep, N. N., Auta, A., & Wannang, N. N. (2011). Antiulcer properties of alkaloids isolated from the pulp of Cucumis metuliferus fruit E. (Cucurbitaceae). International Journal of Pharmaceutical Sciences and Research, 2(10), 2586–2588. http://doi.org/10.13040/IJPSR.0975-8232.2(10).2586-88

Omokhua-Uyi, A. G., & Van Staden, J. (2020). Phytomedicinal relevance of South African Cucurbitaceae species and their safety assessment: A review. Journal of Ethnopharmacology, 259, Article 112967. https://doi.org/10.1016/j.jep.2020.112967

Park, E., Luo, Y., Marine, S. C., Everts, K. L., Micallef, S. A., Bolten, S., & Stommel, J. (2018). Consumer preference and physicochemical evaluation of organically grown melons. Postharvest Biology and Technology, 141, 77–85. https://doi.org/10.1016/j.postharvbio.2018.03.001

Pereira, A. G., Otero, P., Echave, J., Carreira-Casais, A., Chamorro, F, Collazo, N., Jaboui, A., Lourenço-Lopes, C., Simal-Gandara, J., & Prieto, M. A. (2021). Xanthophylls from the Sea: Algae as Source of Bioactive Carotenoids. Marine Drugs, 19(4), Article 188. https://doi.org/10.3390/md19040188

Petrus, A. J. A. (2014). An Approach to the Chemosystematics of the Genus Cucumis L. Oriental Journal of Chemistry, 30(1), 149–154. http://doi.org/10.13005/ojc/300117

Philippi, S. T. (2018). Tabela de composição de alimentos: suporte para decisão nutricional (6th ed.). [Food composition table: support for nutritional decision-making]. Manole.

Promkan, M., Dakeng, S., Chakrabarty, S., Bögler, O., & Patmasiriwat, P. (2013). The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells. PLOS One, 8(2), Article e55732. https://doi.org/10.1371/journal.pone.0055732

Qian, C., Du, T., Sun, S., Liu, W., Zheng, H., & Wang, J. (2022). An integrated learning algorithm for early prediction of melon Harvest. Scientifc Reports, 12, Article 18199. https://doi.org/10.1038/s41598-022-20799-z

Ravindranath, V., Singh, J., Jayaprakasha, G. K., & Patil, B. S. (2021). Optimization of Extraction Solvent and Fast Blue BB Assay for Comparative Analysis of Antioxidant Phenolics from Cucumis melo L. Plants, 10(7), Article 1379. https://doi.org/10.3390/plants10071379

Reis, K. C., Elias, H. H. S, Lima, L. C. O., Silva, J. D., & Pereira, J. (2006). Japonese cucumber (Cucumis sativus L.) submitted of the treatment with cassava starch film. Ciência e Tecnologia de Alimentos, 30(3), 487–493. https://doi.org/10.1590/S1413-70542006000300015

Renner, S. S., Schaefer, H., & Kocyan, A. (2007). Phylogenetics of Cucumis (Cucurbitaceae): Cucumber (C. sativus) belongs in an Asian/Australian clade far from melon (C. melo). BMC Evolutionary and Biology, 7, Article 58. https://doi.org/10.1186/1471-2148-7-58

Revista Cultivar. (2015, November 10). Campo minado [minefield]. Retrieved January 15, 2025, from https://revistacultivar.com.br/artigos/campo-minado

Robinson, R. W., & Decker-Walters, D. S. (1997). Cucurbits (1st ed.). Oxford University Press.

Rodríguez-Pérez, C., Quirantes-Piné, R., Fernández-Gutiérrez, A., & Segura-Carretero, A. (2013). Comparative characterization of phenolic and other polar compounds in Spanish melon cultivars by using high-performance liquid chromatography coupled to electrospray ionization quadrupole-time of flight mass spectrometry. Food Research International, 54(2), 1519–1527. https://doi.org/10.1016/j.foodres.2013.09.011

Salama, A. M., Navarro, L. D., & Dáz, F. E. (1994). Actividad antiinflamatoria, dosis letal 50 y estudio preliminary phytochemical of Cucumis anguria L. Colombian Journal of Chemical-Pharmaceutical Sciences, 22(1), 42–46. https://dialnet.unirioja.es/servlet/articulo?codigo=8112241

Santos, F. F., Avellar, A. V. O., Santos, V. B., & Silva, V. A. (2021). Avaliação do potencial bioativo do maxixe (Cucumis anguria l.) frente às doenças crônicas não transmissíveis [Evaluation of Gherkin’s (Cucumis anguria L.) bioactive potential against non-communicable chronicdiseases]. Perspectivas da Ciência e Tecnologia, 13, 162–173. https://doi.org/10.22407/1984-5693.2021.v13.p.162-173

Schlötterer, C., & Pemberton. J. (1994). The use of microsatellites for genetic analysis of natural populations. In B. Schierwater, B. Streit, G. P. Wagner, & R. DeSalle (Eds.), Molecular Ecology and Evolution: Approaches and Applications (pp. 203–214). Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7527-1_11

Shrivastava, A., & Roy, S. (2013). Cucurbitaceae: A ethnomedicinally important vegetable family. Journal of Medicinal Plants Studies, 1(4), 16–20. https://www.plantsjournal.com/vol1Issue1/Issue_july_2013/7.1.pdf

Silva, E. M., Magalhães, C. S., Randau, K. P. (2023). Botanical description, ethnomedicinal uses, phytochemistry and pharmacological activities of species of the genus Cucumis L.: A review. Diversitas Journal, 8(3), 1470–1485. https://doi.org/10.48017/dj.v8i3.2536

Sood, A., Kaur P., & Gupta R. (2012). Phytochemical screening and antimicrobial assay of various seeds Extract of Cucurbitaceae family. International Journal of Applied Biology and Pharmaceutical Technology, 3(3), 401–409. https://www.fortunejournals.com/ijabpt/pdf/13058-Ruby%20Gupta[1].pdf

Sousa, A. P. B., Lima, F. G. S., & Lima, A. (2015). Propriedades nutricionais do maxixe e do quiabo. Revista Saúde em Foco, 2(1), 113–129. http://www4.unifsa.com.br/revista/index.php/saudeemfoco/article/view/688

South African National Biodiversity Institute. (2013). Biodiversity for life. Flowering Plants of Africa, 63, 2–8. https://www.sanbi.org/wp-content/uploads/2024/05/2013_FPA63.pdf

Swapnil, P., Meena, M., Singh, S. K., Dhuldhaj, U. P., Harish, & Marwal, A. (2021). Vital roles of carotenoids in plants and humans to deteriorate stress with its structure, biosynthesis, metabolic engineering and functional aspects. Current Plant Biology, 26, Article 100203. https://doi.org/10.1016/j.cpb.2021.100203

Tabela Brasileira de Composição dos Alimentos. (2020). Chemical Composition

(Statistical Information). Retrieved June 30, 2025, from https://www.tbca.net.br/base-dados-en/int_statistical_composition.php?cod_produto=BRC0029B

Thiruvengadam, M., & Chung, I. M. (2014). Optimization of factors influencing in vitro flowering of gherkin (Cucumis anguria L.). Acta Biologica Hungarica, 65(1), 72–84. https://doi.org/10.1556/abiol.65.2014.1.7

Usman, J. G., Sodipo, O. A., & Sandabe, U. K. (2014). In vitro antimicrobial activity of Cucumis metuliferus E. Mey. Ex. Naudin fruit extracts against Salmonella gallinarum. International Journal of Phytomedicine, 6(2), 268–274.

Vella, F. M., Cautella, D., & Laratta, B. (2019). Characterization of Polyphenolic Compounds in Cantaloupe Melon By-Products. Foods, 8(6), Article 196. https://doi.org/10.3390/foods8060196

Vieira, E. F, Grosso, C., Rodrigues, F., Moreira, M. M., Fernandes, V. C., & Delerue-Matos, C. (2020). Bioactive Compounds of Horned Melon (Cucumis Metuliferus E. Meyer ex Naudin). In H. N. Murphy & K. Y. Paek (Eds.), Bioactive Compounds in Underutilized Vegetables and Legumes, (pp. 1–21). Springer. https://doi.org/10.1007/978-3-030-44578-2_21-1

VOSviewer. (2023). Distribution of scientific studies of bioactive compounds in

Cucumis L., free images. Retrieved December 12, 2023, from https://www.vosviewer.com/features/highlights

VOSviewer. (2024). Word cloud with the terms most frequently associated with the genus Cucumis L., in scientific literature. Retrieved December 12, 2024, from https://www.vosviewer.com/features/highlights

Wannang, N. N., Gyang, S. S., Omale, S., Dapar, M. L. P., Jiman, N. S., & Anakwe, C. (2010a). The Effect Of Cucumis Metuliferus E Meye (Cucurbitaceae) On Rat Gastric Functions And Mucosa Intergrity. Nigerian Journal of Natural Products and Medicine, 12, 37–39. https://doi.org/10.4314/njnpm.v12i1.45663

Wannang, N. N., Jiman, N. S., Gyang, S. S., Bukar, B. B., & Gotom, S. (2008). Effects of Cucumis metuliferus E Mey. Ex Naud (Cucurbitaceae) fruit extract on some male reproductive parameters in adult rats. African Journal of Pharmacy and Pharmacology, 2(3), 48–51. https://academicjournals.org/journal/AJPP/cited-by-article/872017832214

Wannang, N. N., Kwanashie, H. O., & Ede, S. O. (2010b). Antiviral activity of the fruit extract of Cucumis metuliferus E. Meye (Curcubitaceae) in chicks. African Journal of Basic and Applied Sciences, 2(3–4), 89–93. http://idosi.org/ajbas/ajbas2(3-4)10/5.pdf

Watt, B. K., & Merrill, A. L. (1963). Composition of Foods: Raw, Processed, Prepared. Consumer and Food Economics Research Division, Agricultural Research Service, U.S. Department of Agriculture.

Xin, T., Tian, H., Ma, Y., Wang, S., Yang, L., Li, X., Zhang, M., Chen, C., Wang, H., Li, H., Xu, J. Huang, S., & Yang, X. (2022). Targeted creating new mutants with compact plant architecture using CRISPR/Cas9 genome editing by an optimized genetic transformation procedure in cucurbit plants. Horticulture Research, 9, Article uhab086. https://doi.org/10.1093/hr/uhab086

Yoon, J.-Y., Chung, I.-M., & Thiruvengadam, M. (2015). Evaluation of phenolic compounds, antioxidant and antimicrobial activities from transgenic hairy root cultures of gherkin (Cucumis anguria L.). South African Journal of Botany, 100, 80–86. https://doi.org/10.1016/j.sajb.2015.05.008

Zhang, T., Li, X., Yang, Y., Guo, X., Feng, Q., Dong, X., & Chen, S. (2019). Genetic analysis and QTL mapping of fruit length and diameter in a cucumber (Cucumber sativus L.) recombinant inbred line (RIL) population. Scientia Horticulturae, 250, 214–222. https://doi.org/10.1016/j.scienta.2019.01.062

Zhu, M., Huang, R., Wen, P., Song, Y., He, B., Tan, J., Hao, H., & Wang, H. (2021). Structural characterization and immunological activity of pectin polysaccharide from kiwano (Cucumis metuliferus) peels. Carbohydrate Polymers, 254, Article e117371. https://doi.org/10.1016/j.carbpol.2020.117371

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2025-07-29

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Silva, C. E. da, & Clerici, M. T. P. S. (2025). Contributions of Cucumis L. Genetic diversity to phytochemical bioavailability and its impact on human health: A review. Food Science and Technology, 45. https://doi.org/10.5327/fst.491

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Artigos de Revisão